APRIL IS TESTICULAR CANCER AWARENESS MONTH.

Posted on Apr 13, 2016 in News and Articles

TESTICULAR CANCER, APRIL, 2016

– Also known as germ cell tumors (GCTs): In general, divided into seminoma or non-seminoma GCTs

– Accounts for only about 1% of male cancers in the United States

– The most common malignancy in young men, 15-35 years old

– Median age at diagnosis= 34

– In 2007 there were 8,820 new cases of testicular cancer, while only 340 (4%) of  these patients died of their cancer

  • incidence of GCTs, especially in Caucasian populations, is increasing globally
  • lifetime risk in U.S. Caucasian men about 1 in 230, with rates in African American men and Hispanic men living in the U.S., although less than U.S. Caucasian men, also increasing
  • lifetime risk in Danish men exceeds 1%
  • rates of testicular cancer in industrialized nations about five times higher than in less developed regions of the world
  • Life expectancy of men diagnosed with testicular cancer, beyond the second year post-diagnosis, is nearly identical to the general population

– As with many other cancers, the incidence of non-GCTs is increasing following successful treatment of testicular cancer

  • the 40 year cumulative incidence of a 2nd malignant neoplasm is about one in three
  • treatment related complications such as delayed cardiovascular disease, neuropathy, kidney-hearing-pulmonary related toxicity, have been reported
  • sexual dysfunction and fertility “issues” are also common post treatment

– About 1.4% of men with testicular cancer have a positive family history

–     sons of men with testicular cancer (GCTs) have a 4-6 fold increased risk

–     siblings of men with testicular GCT have a 8-10 fold increased risk

– Therapeutic Options: treatment options beyond the scope of this review, but they are successful in most instances-

CONSULT WITH YOUR HEALTH CARE  PROFESSIONAL